Welcome to the website for the Bellis Lab at Arkanasas State University! Our group studies the genetic code to understand organism interactions with abiotic and biotic environments and how these interactions change across space and over time. We take inspiration from evolutionary genomics, spatial ecology, and machine learning and are particularly interested in novel intersections of these fields to address problems relevant to food security and ecosystem health in a rapidly changing climate.
Here is just a brief overview of some of the new and ongoing projects we are working on at A-State:
Reference-free approaches for population genomics
Following on previous work, the lab is continuing a special focus on coevolutionary genomics of the parasitic witchweed Striga hermonthica and its cereal hosts, which include sorghum, rice, millet, and maize. S. hermonthica is a devastating constraint to food security across much of Africa, and we are leveraging ecological and evolutionary genomic perspectives to help inform sorghum breeding and weed management in smallholder farming systems. The lab is exploring development of new bioinformatic approaches to help characterize population variation 'beyond SNPs' in large and complex plant genomes. Funding: USAID PEER (PI: Steven Runo, USG-supported partner: Emily Bellis)
Machine learning for genomic prediction and gene-environment association mapping
We are also working on approaches for improved understanding and prediction of plant-environment interactions, through integration of machine learning and evolutionary genomic modeling frameworks.
Temporal dynamics of soil microbiome communities
As part of the Arkansas Tallgrass Prairie Collaborative, we are contributing to a study focused on understanding changes in soil microbe communities and impacts on competition dynamics. Funding: Arkansas INBRE.
7. E.S. Bellis, E.A. Kelly, C.M. Lorts, H. Gao, V.L. DeLeo, G. Rouhan, A. Budden, G.B. Bhaskara, Z. Hu, R. Muscarella, M.P. Timko, B. Nebie, S.M. Runo, N.D. Chilcoat, T.E. Juenger, G.P. Morris, C.W. dePamphilis, and J.R. Lasky. (2020). Genomics of sorghum local adaptation to a parasitic plant.PNAS 117: 4243-4251. press
M. Staton, C. Addo-Quaye, [and 29 others including E.S. Bellis]. (Submitted). The Chinese chestnut genome: a reference for species restoration. bioRxiv
W. Zhou, E.S. Bellis, J. Stubblefield, J. Causey, J. Qualls, K. Walker, and X. Huang. (Submitted). Minor QTLs mining through combination of GWAS and machine learning feature selection.
Emily Bellis, Ph.D. (PI)
Emily is from Arkansas and earned a B.S. in Genetics & Biochemistry at Texas A&M University (College Station, TX) in 2010 and a Ph.D. in Integrative Biology in 2017 from Oregon State University (Corvallis, OR), working with Dee Denver. After a short postdoc on population genomics of transposable elements with Sarah Schaack at Reed College (Portland, OR), she worked with Jesse Lasky and Claude dePamphilis at Penn State (State College, PA) as an NSF Postdoctoral Research Fellow in Biology through the National Plant Genome Initiative. She joined A-State in late 2019 and is currently an Assistant Professor of Bioinformatics. In her spare time, she enjoys hiking, knitting, and attempting unsuccessfully to tire out her energetic Border Collie/Aussie, Pascal.
Grace Rutledge (Undergraduate Researcher)
Grace is in her freshman year at A-State majoring in Pre-Professional Biological Sciences. She is working on a project using bioinformatics to study strigolactone receptor presence-absence variation in parasitic witchweed.
Emilio Soriano Chavez (Undergraduate Researcher)
Emilio is a visiting student from the Arkansas State University Queretaro Campus in Mexico, where he is currently a sophomore majoring in Biotechnology and Chemistry. He is currently working on a project to develop new computational models to predict phenotype from environmental and genotype information in maize.
We're always recruiting enthusiastic undergraduate students. Please contact Emily for more information on projects of potential mutual interest.
Ph.D. Students are advised through the Molecular Biosciences program and Master's Students are advised through MBS or Computer Science. Funding for prospective Master's/Ph.D. students is currently limited, but I am a big advocate of co-advising and also happy help students develop applications for independent funding opportunities such as the NSF GRFP. Please contact Emily to discuss particular research projects you might pursue in the lab to help you progress along your desired career path.
10.25.19 Emily is off to the annual Arkansas INBRE conference, in Fayetteville, AR!
You can find me in room 202 of the Arkansas Biosciences Institute on the A-State main campus in Jonesboro, or reach me by email at ebellis[at]astate[dot]edu.